CBD Microdosing to Find Your “Sweet Spot” Dose

What is a “Sweet Spot” Dosage?

Your “sweet spot” dose is the amount of CBD that gives you the desired results that you are looking for. And it’s important to understand that this “sweet spot” is different for each person.

Most people can take 2 aspirin and it will generally be effective for them. But with CBD, everyone’s endocannabinoid system is very different. As a result, CBD oil users need to expect to do their own experimentation to find the CBD dose that is optimal for them.

For many, less is more. We regularly hear from CBD oil users who experience headaches, nauseau or other ill effects when taking CBD. Unfavorable results such as these can often be the result of too high of a dose and the user may benefit from lowering it.

Optimal Dosage for CBD Oil

Smaller doses can save you money and also be more effective than larger ones. They allow you to slowly build a tolerance and maintain proper balance so that you are at less risk of overstimulating your cannabinoid receptors.

One of the most common methods for finding your “sweet spot” dose is called microdosing. CBD microdosing is a technique that involves taking very small amounts of CBD on a regular schedule.

Some important notes before we get into how to microdose:

  1. The microdosing technique is not a way to take CBD every day. It is an approach to take for 2-3 days to figure out your optimal dosage level.
  2. Once you find your optimal dosage level using microdosing, most users switch to taking their optimal dose two or three times per day based on what works best for them.

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How To Microdose With CBD Oil

Here are some specific instructions for how to microdose with CBD to find your “sweet spot” dose. These instructions are based on a system described by Dr. Dustin Sulak in a recent article in Rolling Stone magazine.

  1. Consume 1 drop of CBD oil placed under your tongue. Before consuming, ask yourself 3 questions and answer on a scale of 1 to 10: How easy is it to breathe, how comfortable and calm does your body feel and how easy is it for you to smile authentically, to feel content and grateful. After writing down your scores, take the CBD oil, wait 45 minutes and ask yourself the questions again. If there’s been no change in your scores and you’ve felt no effect, increase the dose by one drop.

  2. Repeat the process over the next few days, increasing the dose by small increments. When you reach a point where you feel a difference after consuming, you’ve found your minimal effective serving size.

  3. At this point, continue raising the dose by tiny amounts. At some point, there will be no further benefit from a higher dose. You’ve established your therapeutic range, and can take the minimum dose. Continue to experiment with the timing of consumption to find what works best for you.
How to Microdose CBD Oil

Other Dosage Notes

  1. Be aware that different CBD oil products have different potencies. One drop of a product with 2,500mg of CBD in a 30ml bottle is 10X as concentrated as one drop of a product with 250mg of CBD in a 30ml bottle. If you have a lower concentration product, you’ll still eventually find your “sweet spot” by using the method above but it will take longer to get there.
  2. If you want to try the method above but have been taking CBD previously, Dr. Sulak recommends that you abstain from CBD for 2 days before starting the process to reset your tolerance.

Other General Tips for Beginners

  1. Be sure to shake your bottle of CBD oil well before taking it.
  2. Place the drop(s) under your tongue and hold it there for at least 30-60 seconds. You want the oil to absorb sublingually into your bloodstream. Don’t just swallow them.
  3. Be patient and don’t get discouraged if you don’t get the immediate results you were hoping for. Many people don’t get measurable results for a couple of weeks.
  4. Keep researching and learning from the experiences of others. There really is no substitute for a commitment to continual learning with CBD as with most things in life.

Resources: CBD Oil Dosing Log

Source: Why Microdosing Is Taking Over Medical Marijuana, Rolling Stone article by Sara Davidson, April 20, 2017

Brian Peterson

Brian Peterson has been a CBD consumer advocate and educator since 2013. He is the founder and managing editor of the CBDOilUsers.com website. He's also the lead administrator of the CBD Oil Users Group, the largest CBD group on Facebook. His passion is educating consumers so that they can make their own decisions when purchasing and using CBD products.

29 Comments
  1. Thank you Brian, yes I was so confused on how to take it but you totally cleared that up for… Greatly appreciated

  2. Wondering if this technique applies to RSO as well? I am finding it hard to figure out my dosing.

  3. Thanks for this info. I read that vaping greatly increases the bioavailability so how do you measure dosage with vaping? Is one puff equal one drop?
    Thank you!

  4. If you don’t get results for several weeks when starting CBD, how does adding 1 drop every 45 minutes help you find your sweet spot? If it takes weeks to build it up in your system, it seems like adding a drop every 45 minutes is overkill. I’m so confused.

  5. Great info, I’m still a little confused though. I just started taking CBD for relieve from migraines I’ve had over 30 years. My bottle is 1000mg/60ml. I started with taking .50 ml 2x per day, but didn’t really notice a change, so this morning I took .75ml in the morning, and another .25ml about an hour later (was feeling a migraine coming on.) What I am confused about is how many milligrams I am taking, as all the measurements I’ve seen on the internet are in milligrams. How can I easily convert this info? Thanks.

  6. I’m glad to have come across your site! I started the oil yesterday and took half of the 1 ml dose and dry heaved cuz it was too oily for my brain to accept, if that makes sense. This morning I took .25 ml dose and it went down fine. I’ve also read some people have greater success continuing with micro-dosing daily instead of going right for the full amount. I’m planning on doing that, once I find my sweet spot 🙂

  7. Wonderful information for a beginner. Thank You

  8. Yes, very helpful article/answers.

  9. If the benefits can take a few weeks to see, how can you really find your sweet spot until after a few weeks. And then there’s the issue of finding the right product. You could be microdosing with an inappropriate product for weeks and then have to start the whole process over again with another product. Can you tell us what contraindications there are for using CBD oil? Thank you!

  10. I can agree with taking a drop every hour during the day to try and find my sweetspot. ..But what about when I want to sleep??? 3 drops of CBD Pure gave me nightmares for 2 nights. Then stopped taking the drops at night. 3 drops of a previous CBD oil taken in the a.m. turned me into an out of energy, just wanted to lay around all day, I would not DARE try to drive.

  11. Once we find the right dose, is that 1x a day or twice a day?

  12. I just tried it today. I put 6 drops in water and drank it. Has anyone ever tried it that way? Is that a no no or is it OK.

    • The issue with just drinking the drops is that it lowers the bioavailability. By placing the drops under your tongue and holding them there for 30-60 seconds, they will absorb sublingually directly into your bloodstream. By swallowing them, they have to go through the digestive system where the oil gets broken down and less gets into your bloodstream. So you’ll have to use more if you swallow them to get the same effect.

  13. Thank you,still learning…

  14. Great article and thanks for posting this!

  15. Great info! Re: the cytochrome P450 enzymes and metabolizing of prescription meds for blood pressure-beta blocker,calcium channel blocker,angiotensin blocker-all extended release and occasional antibiotics and tramadol as needed-what is the recommended timing to allow CBD to be metabolized without interfering with metabolizing of the medications? As I understand it, the result could be elevated concentrations of the drugs. How long does CBD take to metabolize? Is that serving size dependent?.

  16. Wonderful information thank you

  17. So, once you find your sweet spot, do you add all drops together for the day or just the amount from the last hour? And do you start over at some point in the day or the next day?

    • As part of this method, you would add together the number of drops for the day and that would be your daily dose for the next day. So if you took 1 drop every 45 minutes and it took 6 drops to feel a difference, then you would plan on taking 6 drops as a starting serving size the next day. At that point, you would titrate up and/or take another serving only as needed. Experimentation is key since it is so individualized.

  18. This method worked a lot better for me than going with the label recommendations. It helps you understand what works best for you individually.

  19. Thanks for the info.

  20. Thank you for the info. I am having a hard time figuring out what I need to buy for pain. And where to buy it. You probably can’t advise me on this but I’m throwing it out there

  21. very great info helped me to regulate my starting and stopping point..thank you

  22. Awsome article Brian!

  23. Great information especially for first timers

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